What Couples Can Do If Their Blood Genotypes Are Incompatible

Introduction

Genotype is the complete genetic make up of an individual. They’re usually AA, AS, and SS (sickle cell disease). A genotype AS is one that carries the sickle cell trait. In Nigeria, where genetic conditions like sickle cell disease are common 😊, finding out your blood groups / genotypes are not compatible as a couple can be concerning. But don't worry – there are steps that you can take!

These following steps can be taken if your genotypes are incompatible:

 

1. Get Genetic Counseling 

Couples should consider seeing a genetic counselor like those at the National Sickle Cell Centre in Abuja. These experts can help you understand risks of passing traits like sickle cell to kids and plan ahead. They will assess your genotypes, explain potential risks, and discuss available options – like chances of having a child with sickle cell disease or trait.

2. Prenatal Testing

If you're pregnant, prenatal tests like those offered at Lagos University Teaching Hospital can check for issues like sickle cell disease in the baby. Tests like chorionic villus sampling (CVS) help detect genetic conditions early in pregnancy (about 10-13 weeks). Knowing ahead lets you prepare medically and emotionally.

3. Sickle Cell Management

If there's a risk, plan for care such as taking supplements like folic acid, getting proper vaccinations, and pain management like they do at the Sickle Cell Support Group in the hospitals. Understanding symptoms, triggers, and treatments helps to prepare for potential challenges.

4. Build Support Systems

Having family, friends, or groups like the Sickle Cell Association of Nigeria (SOCAAN) helps in coping. Also, connecting with others facing similar issues provides practical tips and reduces stress.

5. Explore Other Options

If blood group incompatibility poses risks, couples can consider alternatives. Some of these alternatives are:

i. IVF with Genetic Testing (PGD)

Preimplantation Genetic Diagnosis (PGD) checks embryos for genetic issues before implantation. This process reduces the risk of passing conditions like sickle cell to the child before he/she is born.

ii. Adoption

Adoption is a great and loving option because it gives a home to a child in need 😊. You can apply to adopt from a Government orphanage home to begin the process of adoption.

iii. Donor Options

Sperm/egg donation: If one partner has issues, donors can be used to minimize the risk of passing these conditions to the child. 

Making the Decision

Talk to experts like Fertility specialists, counselors, or just a visit to the fertility clinic, to help navigate choices. Weigh the pros and cons with these professionals.

In Summary

Incompatible blood groups do not define your future. With the right information and support, you can plan for a healthy child, free from sickle cell anemia. Talk openly with your partner and healthcare provider.

Read also: negative effects of self medication and why you should avoid it.